siRNA, Anti-CAV1, 2'-F/2'-OMe/2'-MOE/LNA-modified(CAT#: SIRGT01579WQ-2OMe)

The product SIRGT01579WQ-2OMe is a type of small interfering RNA (siRNA) that targets CAV1 gene and regulates the expression of gene. The siRNA interferes with the expression of CAV1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001172895.1; NM_001172896.1; NM_001172897.1; NM_001753.4
Alternative Names BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21
Related Diseases Berardinelli-Seip congenital lipodystrophy
Purification HPLC
Target Gene
Gene ID 857
Uniprot ID Q03135
Sub Cat Target Species Modification Scale  
SIRGT02579WQ-2F CAV1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03579WQ-2MOE CAV1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04579WQ-LNA CAV1 Human Locked Nucleic Acid (LNA) Inquiry

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