siRNA, Anti-CBX5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT36972WQ-2OMe)

The product SIRGT36972WQ-2OMe is a type of small interfering RNA (siRNA) that targets CBX5 gene and regulates the expression of gene. The siRNA interferes with the expression of CBX5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001127321.1
Alternative Names HEL25; HP1; HP1A
Related Diseases Reynolds Syndrome
Purification HPLC
Target Gene
Gene ID 23468
Uniprot ID P45973
Sub Cat Target Species Modification Scale  
SIRGT37972WQ-2F CBX5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT38972WQ-2MOE CBX5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT39972WQ-LNA CBX5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT36972WQ-RB CBX5 Human Ribo-modified Inquiry
SIRGT37972WQ-BB CBX5 Human Backbone-modified Inquiry

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