siRNA, Anti-CCND2, 2'-F/2'-OMe/2'-MOE/LNA/Backbone-modified(CAT#: SIRGT01604WQ-2OMe)

The product SIRGT01604WQ-2OMe is a type of small interfering RNA (siRNA) that targets CCND2 gene and regulates the expression of gene. The siRNA interferes with the expression of CCND2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001759.3
Alternative Names KIAK0002; MPPH3
Related Diseases Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3)
Purification HPLC
Target Gene
Gene ID 894
Uniprot ID P30279
Sub Cat Target Species Modification Scale  
SIRGT02604WQ-2F CCND2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03604WQ-2MOE CCND2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04604WQ-LNA CCND2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT02604WQ-BB CCND2 Human Backbone-modified Inquiry

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