siRNA, Anti-CD180, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11638WQ-2OMe)

The product SIRGT11638WQ-2OMe is a type of small interfering RNA (siRNA) that targets CD180 gene and regulates the expression of gene. The siRNA interferes with the expression of CD180 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005582.2
Alternative Names LY64; Ly78; RP105
Related Diseases Systemic Lupus Erythematosus
Purification HPLC
Target Gene
Gene ID 4064
Uniprot ID Q99467
Sub Cat Target Species Modification Scale  
SIRGT12638WQ-2F CD180 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13638WQ-2MOE CD180 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14638WQ-LNA CD180 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11638WQ-RB CD180 Human Ribo-modified Inquiry
SIRGT12638WQ-BB CD180 Human Backbone-modified Inquiry

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