siRNA, Anti-CD3D, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01620WQ-2OMe)

The product SIRGT01620WQ-2OMe is a type of small interfering RNA (siRNA) that targets CD3D gene and regulates the expression of gene. The siRNA interferes with the expression of CD3D gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000732.4; NM_001040651.1
Alternative Names CD3-DELTA; IMD19; T3D
Related Diseases Immunodeficiency
Purification HPLC
Target Gene
Gene ID 915
Uniprot ID P04234
Sub Cat Target Species Modification Scale  
SIRGT02620WQ-2F CD3D Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03620WQ-2MOE CD3D Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04620WQ-LNA CD3D Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01620WQ-RB CD3D Human Ribo-modified Inquiry
SIRGT02620WQ-BB CD3D Human Backbone-modified Inquiry

Related Products