siRNA, Anti-CDH2, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT01690WQ-2OMe)

The product SIRGT01690WQ-2OMe is a type of small interfering RNA (siRNA) that targets CDH2 gene and regulates the expression of gene. The siRNA interferes with the expression of CDH2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001308176.1; NM_001792.4
Alternative Names CD325; CDHN; CDw325; NCAD
Related Diseases Arrhythmogenic Right Ventricular Cardiomyopathy, Malignant Pleural Mesothelioma
Purification HPLC
Target Gene
Gene ID 1000
Uniprot ID P19022
Sub Cat Target Species Modification Scale  
SIRGT02690WQ-2F CDH2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT04690WQ-LNA CDH2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01690WQ-RB CDH2 Human Ribo-modified Inquiry
SIRGT02690WQ-BB CDH2 Human Backbone-modified Inquiry

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