siRNA, Anti-CDK5R1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT26618WQ-2OMe)

The product SIRGT26618WQ-2OMe is a type of small interfering RNA (siRNA) that targets CDK5R1 gene and regulates the expression of gene. The siRNA interferes with the expression of CDK5R1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003885.2
Alternative Names CDK5P35; CDK5R; NCK5A; p23; p25; p35; p35nck5a
Related Diseases Alzheimer's disease
Purification HPLC
Target Gene
Gene ID 8851
Uniprot ID Q15078
Sub Cat Target Species Modification Scale  
SIRGT27618WQ-2F CDK5R1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28618WQ-2MOE CDK5R1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29618WQ-LNA CDK5R1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26618WQ-RB CDK5R1 Human Ribo-modified Inquiry
SIRGT27618WQ-BB CDK5R1 Human Backbone-modified Inquiry

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