siRNA, Anti-CDR1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01721WQ-2OMe)

The product SIRGT01721WQ-2OMe is a type of small interfering RNA (siRNA) that targets CDR1 gene and regulates the expression of gene. The siRNA interferes with the expression of CDR1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004065.2
Alternative Names CDR; CDR34; CDR62A
Related Diseases Cerebellar Degeneration
Purification HPLC
Target Gene
Gene ID 1038
Uniprot ID P51861
Sub Cat Target Species Modification Scale  
SIRGT02721WQ-2F CDR1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03721WQ-2MOE CDR1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04721WQ-LNA CDR1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01721WQ-RB CDR1 Human Ribo-modified Inquiry
SIRGT02721WQ-BB CDR1 Human Backbone-modified Inquiry

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