siRNA, Anti-CEP350, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31350WQ-2OMe)
The product SIRGT31350WQ-2OMe is a type of small interfering RNA (siRNA) that targets CEP350 gene and regulates the expression of gene. The siRNA interferes with the expression of CEP350 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_014810.4 |
| Alternative Names | CAP350; GM133 |
| Related Diseases | Epidermal Appendage Tumor |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT32350WQ-2F | CEP350 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT33350WQ-2MOE | CEP350 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT34350WQ-LNA | CEP350 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT31350WQ-RB | CEP350 | Human | Ribo-modified | ||
| SIRGT32350WQ-BB | CEP350 | Human | Backbone-modified |