siRNA, Anti-CIAO1, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT26979WQ-2OMe)

The product SIRGT26979WQ-2OMe is a type of small interfering RNA (siRNA) that targets CIAO1 gene and regulates the expression of gene. The siRNA interferes with the expression of CIAO1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004804.2
Alternative Names CIA1; WDR39
Related Diseases Xeroderma Pigmentosum, Variant Type
Purification HPLC
Target Gene
Gene ID 9391
Uniprot ID O76071
Sub Cat Target Species Modification Scale  
SIRGT27979WQ-2F CIAO1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT29979WQ-LNA CIAO1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26979WQ-RB CIAO1 Human Ribo-modified Inquiry
SIRGT27979WQ-BB CIAO1 Human Backbone-modified Inquiry

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