siRNA, Anti-CISH, 2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT01800WQ-2OMe)

The product SIRGT01800WQ-2OMe is a type of small interfering RNA (siRNA) that targets CISH gene and regulates the expression of gene. The siRNA interferes with the expression of CISH gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_013324.5; NM_145071.2
Alternative Names BACTS2; CIS; CIS-1; G18; SOCS
Related Diseases Bacteremia, Malaria
Purification HPLC
Target Gene
Gene ID 1154
Uniprot ID Q9NSE2
Sub Cat Target Species Modification Scale  
SIRGT04800WQ-LNA CISH Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01800WQ-RB CISH Human Ribo-modified Inquiry
SIRGT02800WQ-BB CISH Human Backbone-modified Inquiry

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