siRNA, Anti-CKB, 2'-F/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT02798WQ-2F)

The product SIRGT02798WQ-2F is a type of small interfering RNA (siRNA) that targets CKB gene and regulates the expression of gene. The siRNA interferes with the expression of CKB gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001823.4
Alternative Names B-CK; BCK; CKBB; HEL-211; HEL-S-29
Related Diseases Subendocardial Myocardial Infarction, Macular Telangiectasia Type 2
Purification HPLC
Target Gene
Gene ID 1152
Uniprot ID P12277
Sub Cat Target Species Modification Scale  
SIRGT03798WQ-2MOE CKB Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04798WQ-LNA CKB Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01798WQ-RB CKB Human Ribo-modified Inquiry
SIRGT02798WQ-BB CKB Human Backbone-modified Inquiry

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