siRNA, Anti-CKB, 2'-F/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT02798WQ-2F)
The product SIRGT02798WQ-2F is a type of small interfering RNA (siRNA) that targets CKB gene and regulates the expression of gene. The siRNA interferes with the expression of CKB gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001823.4 |
| Alternative Names | B-CK; BCK; CKBB; HEL-211; HEL-S-29 |
| Related Diseases | Subendocardial Myocardial Infarction, Macular Telangiectasia Type 2 |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT03798WQ-2MOE | CKB | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT04798WQ-LNA | CKB | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT01798WQ-RB | CKB | Human | Ribo-modified | ||
| SIRGT02798WQ-BB | CKB | Human | Backbone-modified |