siRNA, Anti-CLCA4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT36481WQ-2OMe)

The product SIRGT36481WQ-2OMe is a type of small interfering RNA (siRNA) that targets CLCA4 gene and regulates the expression of gene. The siRNA interferes with the expression of CLCA4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_012128.3
Alternative Names CaCC; CaCC2
Related Diseases Cystic Fibrosis and Cecum Carcinoma
Purification HPLC
Target Gene
Gene ID 22802
Uniprot ID Q14CN2
Sub Cat Target Species Modification Scale  
SIRGT37481WQ-2F CLCA4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT38481WQ-2MOE CLCA4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT39481WQ-LNA CLCA4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT36481WQ-RB CLCA4 Human Ribo-modified Inquiry
SIRGT37481WQ-BB CLCA4 Human Backbone-modified Inquiry

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