siRNA, Anti-CLOCK, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT31118WQ-2OMe)

The product SIRGT31118WQ-2OMe is a type of small interfering RNA (siRNA) that targets CLOCK gene and regulates the expression of gene. The siRNA interferes with the expression of CLOCK gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001267843.1; NM_004898.3
Alternative Names KAT13D; bHLHe8
Related Diseases Delayed Sleep Phase Disorder
Purification HPLC
Target Gene
Gene ID 9575
Uniprot ID O15516
Sub Cat Target Species Modification Scale  
SIRGT32118WQ-2F CLOCK Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33118WQ-2MOE CLOCK Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT31118WQ-RB CLOCK Human Ribo-modified Inquiry
SIRGT32118WQ-BB CLOCK Human Backbone-modified Inquiry

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