siRNA, Anti-CNTF, 2'-F/2'-OMe/2'-MOE/Ribo-modified(CAT#: SIRGT01859WQ-2OMe)

The product SIRGT01859WQ-2OMe is a type of small interfering RNA (siRNA) that targets CNTF gene and regulates the expression of gene. The siRNA interferes with the expression of CNTF gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000614.3
Alternative Names HCNTF
Related Diseases Motor Neuron Disease, Retinal Degeneration
Purification HPLC
Target Gene
Gene ID 1270
Uniprot ID P26441
Sub Cat Target Species Modification Scale  
SIRGT02859WQ-2F CNTF Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03859WQ-2MOE CNTF Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT01859WQ-RB CNTF Human Ribo-modified Inquiry

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