siRNA, Anti-CNTFR, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01860WQ-2OMe)

The product SIRGT01860WQ-2OMe is a type of small interfering RNA (siRNA) that targets CNTFR gene and regulates the expression of gene. The siRNA interferes with the expression of CNTFR gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001207011.1; NM_001842.4; NM_147164.2
Related Diseases Cold-Induced Sweating Syndrome
Purification HPLC
Target Gene
Gene ID 1271
Uniprot ID P26992
Sub Cat Target Species Modification Scale  
SIRGT02860WQ-2F CNTFR Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03860WQ-2MOE CNTFR Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04860WQ-LNA CNTFR Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01860WQ-RB CNTFR Human Ribo-modified Inquiry
SIRGT02860WQ-BB CNTFR Human Backbone-modified Inquiry

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