siRNA, Anti-COBL, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT36804WQ-2OMe)

The product SIRGT36804WQ-2OMe is a type of small interfering RNA (siRNA) that targets COBL gene and regulates the expression of gene. The siRNA interferes with the expression of COBL gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001287436.2
Related Diseases Chromosome 22Q11.2 Deletion Syndrome, Distal
Purification HPLC
Target Gene
Gene ID 23242
Uniprot ID O75128
Sub Cat Target Species Modification Scale  
SIRGT37804WQ-2F COBL Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT38804WQ-2MOE COBL Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT39804WQ-LNA COBL Human Locked Nucleic Acid (LNA) Inquiry
SIRGT36804WQ-RB COBL Human Ribo-modified Inquiry
SIRGT37804WQ-BB COBL Human Backbone-modified Inquiry

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