siRNA, Anti-COL10A1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01883WQ-2OMe)

The product SIRGT01883WQ-2OMe is a type of small interfering RNA (siRNA) that targets COL10A1 gene and regulates the expression of gene. The siRNA interferes with the expression of COL10A1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000493.3
Related Diseases Schmid type metaphyseal chondrodysplasia (SMCD)
Purification HPLC
Target Gene
Gene ID 1300
Uniprot ID Q03692
Sub Cat Target Species Modification Scale  
SIRGT02883WQ-2F COL10A1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03883WQ-2MOE COL10A1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04883WQ-LNA COL10A1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01883WQ-RB COL10A1 Human Ribo-modified Inquiry
SIRGT02883WQ-BB COL10A1 Human Backbone-modified Inquiry

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