siRNA, Anti-COL4A1, 2'-F/2'-OMe/2'-MOE/LNA/Backbone-modified(CAT#: SIRGT01866WQ-2OMe)

The product SIRGT01866WQ-2OMe is a type of small interfering RNA (siRNA) that targets COL4A1 gene and regulates the expression of gene. The siRNA interferes with the expression of COL4A1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001303110.1; NM_001845.5
Alternative Names BSVD; RATOR
Related Diseases Porencephaly, Cerebrovascular disease, Renal and muscular defects
Purification HPLC
Target Gene
Gene ID 1282
Uniprot ID P02462
Sub Cat Target Species Modification Scale  
SIRGT02866WQ-2F COL4A1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03866WQ-2MOE COL4A1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04866WQ-LNA COL4A1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT02866WQ-BB COL4A1 Human Backbone-modified Inquiry

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