siRNA, Anti-COL4A2, 2'-OMe/2'-MOE/Backbone-modified(CAT#: SIRGT01867WQ-2OMe)

The product SIRGT01867WQ-2OMe is a type of small interfering RNA (siRNA) that targets COL4A2 gene and regulates the expression of gene. The siRNA interferes with the expression of COL4A2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001846.3
Alternative Names ICH; POREN2
Related Diseases Brain Small Vessel Disease, Hemorrhage
Purification HPLC
Target Gene
Gene ID 1284
Uniprot ID P08572
Sub Cat Target Species Modification Scale  
SIRGT03867WQ-2MOE COL4A2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT02867WQ-BB COL4A2 Human Backbone-modified Inquiry

Related Products