siRNA, Anti-COL4A5, 2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01870WQ-2OMe)

The product SIRGT01870WQ-2OMe is a type of small interfering RNA (siRNA) that targets COL4A5 gene and regulates the expression of gene. The siRNA interferes with the expression of COL4A5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000495.4; NM_033380.2
Alternative Names ASLN; ATS; CA54
Related Diseases Alport Syndrome
Purification HPLC
Target Gene
Gene ID 1287
Uniprot ID P29400
Sub Cat Target Species Modification Scale  
SIRGT03870WQ-2MOE COL4A5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04870WQ-LNA COL4A5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01870WQ-RB COL4A5 Human Ribo-modified Inquiry
SIRGT02870WQ-BB COL4A5 Human Backbone-modified Inquiry

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