siRNA, Anti-COL6A2, 2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT01875WQ-2OMe)

The product SIRGT01875WQ-2OMe is a type of small interfering RNA (siRNA) that targets COL6A2 gene and regulates the expression of gene. The siRNA interferes with the expression of COL6A2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001849.3; NM_058174.2; NM_058175.2
Alternative Names BTHLM1; PP3610; UCMD1
Related Diseases Bethlem myopathy, Ullrich scleroatonic muscular dystrophy
Purification HPLC
Target Gene
Gene ID 1292
Uniprot ID P12110
Sub Cat Target Species Modification Scale  
SIRGT04875WQ-LNA COL6A2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01875WQ-RB COL6A2 Human Ribo-modified Inquiry
SIRGT02875WQ-BB COL6A2 Human Backbone-modified Inquiry

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