siRNA, Anti-COL8A1, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT01878WQ-2OMe)

The product SIRGT01878WQ-2OMe is a type of small interfering RNA (siRNA) that targets COL8A1 gene and regulates the expression of gene. The siRNA interferes with the expression of COL8A1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001850.4; NM_020351.3
Alternative Names C3orf7
Related Diseases Corneal Endothelial Dystrophy
Purification HPLC
Target Gene
Gene ID 1295
Uniprot ID P27658
Sub Cat Target Species Modification Scale  
SIRGT02878WQ-2F COL8A1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03878WQ-2MOE COL8A1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT01878WQ-RB COL8A1 Human Ribo-modified Inquiry
SIRGT02878WQ-BB COL8A1 Human Backbone-modified Inquiry

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