siRNA, Anti-COTL1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT36931WQ-2OMe)

The product SIRGT36931WQ-2OMe is a type of small interfering RNA (siRNA) that targets COTL1 gene and regulates the expression of gene. The siRNA interferes with the expression of COTL1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_021149.3
Alternative Names CLP
Related Diseases Lung Cancer and Clivus Chordoma
Purification HPLC
Target Gene
Gene ID 23406
Uniprot ID Q14019
Sub Cat Target Species Modification Scale  
SIRGT37931WQ-2F COTL1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT38931WQ-2MOE COTL1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT39931WQ-LNA COTL1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT36931WQ-RB COTL1 Human Ribo-modified Inquiry
SIRGT37931WQ-BB COTL1 Human Backbone-modified Inquiry

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