siRNA, Anti-COX10, 2'-F/2'-OMe/2'-MOE/LNA/Backbone-modified(CAT#: SIRGT01911WQ-2OMe)

The product SIRGT01911WQ-2OMe is a type of small interfering RNA (siRNA) that targets COX10 gene and regulates the expression of gene. The siRNA interferes with the expression of COX10 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001303.3
Related Diseases CMT1A (Charcot-Marie-Tooth type 1A)
Purification HPLC
Target Gene
Gene ID 1352
Uniprot ID Q12887
Sub Cat Target Species Modification Scale  
SIRGT02911WQ-2F COX10 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03911WQ-2MOE COX10 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04911WQ-LNA COX10 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT02911WQ-BB COX10 Human Backbone-modified Inquiry

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