siRNA, Anti-COX5A, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT26971WQ-2OMe)

The product SIRGT26971WQ-2OMe is a type of small interfering RNA (siRNA) that targets COX5A gene and regulates the expression of gene. The siRNA interferes with the expression of COX5A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004255.3
Alternative Names COX; COX-VA; VA
Related Diseases Mitochondrial Complex Iv Deficiency
Purification HPLC
Target Gene
Gene ID 9377
Uniprot ID P20674
Sub Cat Target Species Modification Scale  
SIRGT27971WQ-2F COX5A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28971WQ-2MOE COX5A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29971WQ-LNA COX5A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26971WQ-RB COX5A Human Ribo-modified Inquiry
SIRGT27971WQ-BB COX5A Human Backbone-modified Inquiry

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