siRNA, Anti-COX5B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01901WQ-2OMe)

The product SIRGT01901WQ-2OMe is a type of small interfering RNA (siRNA) that targets COX5B gene and regulates the expression of gene. The siRNA interferes with the expression of COX5B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001862.2
Alternative Names COXVB
Related Diseases Mitochondrial Complex I Deficiency
Purification HPLC
Target Gene
Gene ID 1329
Uniprot ID P10606
Sub Cat Target Species Modification Scale  
SIRGT02901WQ-2F COX5B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03901WQ-2MOE COX5B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04901WQ-LNA COX5B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01901WQ-RB COX5B Human Ribo-modified Inquiry
SIRGT02901WQ-BB COX5B Human Backbone-modified Inquiry

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