siRNA, Anti-CR1L, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01934WQ-2OMe)

The product SIRGT01934WQ-2OMe is a type of small interfering RNA (siRNA) that targets CR1L gene and regulates the expression of gene. The siRNA interferes with the expression of CR1L gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_175710.1
Related Diseases Cortisone Reductase Deficiency
Purification HPLC
Target Gene
Gene ID 1379
Uniprot ID Q2VPA4
Sub Cat Target Species Modification Scale  
SIRGT02934WQ-2F CR1L Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03934WQ-2MOE CR1L Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04934WQ-LNA CR1L Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01934WQ-RB CR1L Human Ribo-modified Inquiry
SIRGT02934WQ-BB CR1L Human Backbone-modified Inquiry

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