siRNA, Anti-CRK, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01948WQ-2OMe)

The product SIRGT01948WQ-2OMe is a type of small interfering RNA (siRNA) that targets CRK gene and regulates the expression of gene. The siRNA interferes with the expression of CRK gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005206.4; NM_016823.3
Alternative Names CRKII; p38
Related Diseases Sarcoma, Duplication Syndrome
Purification HPLC
Target Gene
Gene ID 1398
Uniprot ID P46108
Sub Cat Target Species Modification Scale  
SIRGT02948WQ-2F CRK Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03948WQ-2MOE CRK Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04948WQ-LNA CRK Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01948WQ-RB CRK Human Ribo-modified Inquiry
SIRGT02948WQ-BB CRK Human Backbone-modified Inquiry

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