siRNA, Anti-CRYAB, LNA-modified(CAT#: SIRGT04956WQ-LNA)

The product SIRGT04956WQ-LNA is a type of small interfering RNA (siRNA) that targets CRYAB gene and regulates the expression of gene. The siRNA interferes with the expression of CRYAB gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification Locked Nucleic Acid (LNA)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_001289807.1; NM_001289808.1; NM_001330379.1; NM_001885.2
Alternative Names CMD1II; CRYA2; CTPP2; CTRCT16; HEL-S-101; HSPB5; MFM2
Related Diseases Myopathy, Cardiomyopathy
Purification HPLC
Target Gene
Gene ID 1410
Uniprot ID P02511

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