siRNA, Anti-CRYBA1, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT01957WQ-2OMe)

The product SIRGT01957WQ-2OMe is a type of small interfering RNA (siRNA) that targets CRYBA1 gene and regulates the expression of gene. The siRNA interferes with the expression of CRYBA1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005208.4
Alternative Names CRYB1; CTRCT10
Related Diseases Early-Onset Sutural Cataract
Purification HPLC
Target Gene
Gene ID 1411
Uniprot ID P05813
Sub Cat Target Species Modification Scale  
SIRGT02957WQ-2F CRYBA1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03957WQ-2MOE CRYBA1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT01957WQ-RB CRYBA1 Human Ribo-modified Inquiry
SIRGT02957WQ-BB CRYBA1 Human Backbone-modified Inquiry

Related Products