siRNA, Anti-CRYBA2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01958WQ-2OMe)

The product SIRGT01958WQ-2OMe is a type of small interfering RNA (siRNA) that targets CRYBA2 gene and regulates the expression of gene. The siRNA interferes with the expression of CRYBA2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_057093.1; NM_057094.1
Alternative Names CTRCT42
Related Diseases Cataract
Purification HPLC
Target Gene
Gene ID 1412
Uniprot ID P53672
Sub Cat Target Species Modification Scale  
SIRGT02958WQ-2F CRYBA2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03958WQ-2MOE CRYBA2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04958WQ-LNA CRYBA2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01958WQ-RB CRYBA2 Human Ribo-modified Inquiry
SIRGT02958WQ-BB CRYBA2 Human Backbone-modified Inquiry

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