siRNA, Anti-CRYGA, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01963WQ-2OMe)

The product SIRGT01963WQ-2OMe is a type of small interfering RNA (siRNA) that targets CRYGA gene and regulates the expression of gene. The siRNA interferes with the expression of CRYGA gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_014617.3
Alternative Names CRY-g-A; CRYG1; CRYG5
Related Diseases Cataract, Scleral Staphyloma
Purification HPLC
Target Gene
Gene ID 1418
Uniprot ID P11844
Sub Cat Target Species Modification Scale  
SIRGT02963WQ-2F CRYGA Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03963WQ-2MOE CRYGA Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04963WQ-LNA CRYGA Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01963WQ-RB CRYGA Human Ribo-modified Inquiry
SIRGT02963WQ-BB CRYGA Human Backbone-modified Inquiry

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