siRNA, Anti-CRYM, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01968WQ-2OMe)

The product SIRGT01968WQ-2OMe is a type of small interfering RNA (siRNA) that targets CRYM gene and regulates the expression of gene. The siRNA interferes with the expression of CRYM gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001888.4
Alternative Names DFNA40; THBP
Related Diseases Autosomal dominant non-syndromic deafness
Purification HPLC
Target Gene
Gene ID 1428
Uniprot ID Q14894
Sub Cat Target Species Modification Scale  
SIRGT02968WQ-2F CRYM Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03968WQ-2MOE CRYM Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04968WQ-LNA CRYM Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01968WQ-RB CRYM Human Ribo-modified Inquiry
SIRGT02968WQ-BB CRYM Human Backbone-modified Inquiry

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