siRNA, Anti-CSNK1G3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01988WQ-2OMe)
The product SIRGT01988WQ-2OMe is a type of small interfering RNA (siRNA) that targets CSNK1G3 gene and regulates the expression of gene. The siRNA interferes with the expression of CSNK1G3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001031812.3; NM_001044723.2; NM_001270572.1; NM_001270573.1; NM_001270574.1; NM_004384.4 |
| Alternative Names | CKI-gamma 3; CSNK1G3L |
| Related Diseases | Hedgehog signaling events mediated by Gli proteins |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT02988WQ-2F | CSNK1G3 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT03988WQ-2MOE | CSNK1G3 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT04988WQ-LNA | CSNK1G3 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT01988WQ-RB | CSNK1G3 | Human | Ribo-modified | ||
| SIRGT02988WQ-BB | CSNK1G3 | Human | Backbone-modified |
