siRNA, Anti-CTC1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46431WQ-2OMe)

The product SIRGT46431WQ-2OMe is a type of small interfering RNA (siRNA) that targets CTC1 gene and regulates the expression of gene. The siRNA interferes with the expression of CTC1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_025099.5
Alternative Names AAF-132; AAF132; C17orf68; CRMCC; tmp494178
Related Diseases Dyskeratosis Congenita
Purification HPLC
Target Gene
Gene ID 80169
Uniprot ID Q2NKJ3
Sub Cat Target Species Modification Scale  
SIRGT47431WQ-2F CTC1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48431WQ-2MOE CTC1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49431WQ-LNA CTC1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46431WQ-RB CTC1 Human Ribo-modified Inquiry
SIRGT47431WQ-BB CTC1 Human Backbone-modified Inquiry

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