siRNA, Anti-CTNS, 2'-F/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT07018WQ-2F)

The product SIRGT07018WQ-2F is a type of small interfering RNA (siRNA) that targets CTNS gene and regulates the expression of gene. The siRNA interferes with the expression of CTNS gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001031681.2; NM_004937.2
Alternative Names CTNS-LSB; PQLC4
Related Diseases Cystinosis
Purification HPLC
Target Gene
Gene ID 1497
Uniprot ID O60931
Sub Cat Target Species Modification Scale  
SIRGT08018WQ-2MOE CTNS Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09018WQ-LNA CTNS Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06018WQ-RB CTNS Human Ribo-modified Inquiry
SIRGT07018WQ-BB CTNS Human Backbone-modified Inquiry

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