siRNA, Anti-CYP17A1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06074WQ-2OMe)

The product SIRGT06074WQ-2OMe is a type of small interfering RNA (siRNA) that targets CYP17A1 gene and regulates the expression of gene. The siRNA interferes with the expression of CYP17A1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000102.3
Alternative Names CPT7; CYP17; P450C17; S17AH
Related Diseases Pseudohermaphroditism, Adrenal hyperplasia
Purification HPLC
Target Gene
Gene ID 1586
Uniprot ID P05093
Sub Cat Target Species Modification Scale  
SIRGT07074WQ-2F CYP17A1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08074WQ-2MOE CYP17A1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09074WQ-LNA CYP17A1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06074WQ-RB CYP17A1 Human Ribo-modified Inquiry
SIRGT07074WQ-BB CYP17A1 Human Backbone-modified Inquiry

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