siRNA, Anti-CYP46A1, 2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT36114WQ-2OMe)

The product SIRGT36114WQ-2OMe is a type of small interfering RNA (siRNA) that targets CYP46A1 gene and regulates the expression of gene. The siRNA interferes with the expression of CYP46A1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_006668.1
Alternative Names CP46; CYP46
Related Diseases Alzheimer Disease, Multidrug-Resistant Tuberculosis
Purification HPLC
Target Gene
Gene ID 10858
Uniprot ID Q9Y6A2
Sub Cat Target Species Modification Scale  
SIRGT39114WQ-LNA CYP46A1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT36114WQ-RB CYP46A1 Human Ribo-modified Inquiry
SIRGT37114WQ-BB CYP46A1 Human Backbone-modified Inquiry

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