siRNA, Anti-CYP51A1, 2'-F/2'-OMe/2'-MOE/LNA-modified(CAT#: SIRGT06080WQ-2OMe)

The product SIRGT06080WQ-2OMe is a type of small interfering RNA (siRNA) that targets CYP51A1 gene and regulates the expression of gene. The siRNA interferes with the expression of CYP51A1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000786.3; NM_001146152.1
Alternative Names CP51; CYP51; CYPL1; LDM; P450-14DM; P450L1
Related Diseases Chagas Disease
Purification HPLC
Target Gene
Gene ID 1595
Uniprot ID Q16850
Sub Cat Target Species Modification Scale  
SIRGT07080WQ-2F CYP51A1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08080WQ-2MOE CYP51A1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09080WQ-LNA CYP51A1 Human Locked Nucleic Acid (LNA) Inquiry

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