siRNA, Anti-DBN1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06100WQ-2OMe)

The product SIRGT06100WQ-2OMe is a type of small interfering RNA (siRNA) that targets DBN1 gene and regulates the expression of gene. The siRNA interferes with the expression of DBN1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004395.3; NM_080881.2
Alternative Names D0S117E
Related Diseases Alzheimer's disease
Purification HPLC
Target Gene
Gene ID 1627
Uniprot ID Q16643
Sub Cat Target Species Modification Scale  
SIRGT07100WQ-2F DBN1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08100WQ-2MOE DBN1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09100WQ-LNA DBN1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06100WQ-RB DBN1 Human Ribo-modified Inquiry
SIRGT07100WQ-BB DBN1 Human Backbone-modified Inquiry

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