siRNA, Anti-DDX17, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31875WQ-2OMe)

The product SIRGT31875WQ-2OMe is a type of small interfering RNA (siRNA) that targets DDX17 gene and regulates the expression of gene. The siRNA interferes with the expression of DDX17 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001098504.1; NM_006386.4
Alternative Names P72; RH70
Related Diseases Retinitis Pigmentosa 54
Purification HPLC
Target Gene
Gene ID 10521
Uniprot ID Q92841
Sub Cat Target Species Modification Scale  
SIRGT32875WQ-2F DDX17 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33875WQ-2MOE DDX17 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34875WQ-LNA DDX17 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31875WQ-RB DDX17 Human Ribo-modified Inquiry
SIRGT32875WQ-BB DDX17 Human Backbone-modified Inquiry

Related Products