siRNA, Anti-DEFA6, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT06133WQ-2OMe)

The product SIRGT06133WQ-2OMe is a type of small interfering RNA (siRNA) that targets DEFA6 gene and regulates the expression of gene. The siRNA interferes with the expression of DEFA6 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001926.3
Alternative Names DEF6; HD-6
Related Diseases Acute Vascular Insufficiency Of Intestine
Purification HPLC
Target Gene
Gene ID 1671
Uniprot ID Q01524
Sub Cat Target Species Modification Scale  
SIRGT07133WQ-2F DEFA6 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08133WQ-2MOE DEFA6 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT06133WQ-RB DEFA6 Human Ribo-modified Inquiry
SIRGT07133WQ-BB DEFA6 Human Backbone-modified Inquiry

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