siRNA, Anti-DEFB1, 2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT06134WQ-2OMe)

The product SIRGT06134WQ-2OMe is a type of small interfering RNA (siRNA) that targets DEFB1 gene and regulates the expression of gene. The siRNA interferes with the expression of DEFB1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005218.3
Alternative Names BD1; DEFB-1; DEFB101; HBD1
Related Diseases Tonsillitis, Cystic Fibrosis
Purification HPLC
Target Gene
Gene ID 1672
Uniprot ID P60022
Sub Cat Target Species Modification Scale  
SIRGT09134WQ-LNA DEFB1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06134WQ-RB DEFB1 Human Ribo-modified Inquiry
SIRGT07134WQ-BB DEFB1 Human Backbone-modified Inquiry

Related Products