siRNA, Anti-DET1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41508WQ-2OMe)

The product SIRGT41508WQ-2OMe is a type of small interfering RNA (siRNA) that targets DET1 gene and regulates the expression of gene. The siRNA interferes with the expression of DET1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001144074.2
Related Diseases Hydrolethalus Syndrome 1
Purification HPLC
Target Gene
Gene ID 55070
Uniprot ID Q7L5Y6
Sub Cat Target Species Modification Scale  
SIRGT42508WQ-2F DET1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43508WQ-2MOE DET1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44508WQ-LNA DET1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41508WQ-RB DET1 Human Ribo-modified Inquiry
SIRGT42508WQ-BB DET1 Human Backbone-modified Inquiry

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