siRNA, Anti-DGAT1, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT26499WQ-2OMe)

The product SIRGT26499WQ-2OMe is a type of small interfering RNA (siRNA) that targets DGAT1 gene and regulates the expression of gene. The siRNA interferes with the expression of DGAT1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_012079.5
Alternative Names ARAT; ARGP1; DGAT; DIAR7
Related Diseases Obesity and other metabolic diseases
Purification HPLC
Target Gene
Gene ID 8694
Uniprot ID O75907
Sub Cat Target Species Modification Scale  
SIRGT27499WQ-2F DGAT1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28499WQ-2MOE DGAT1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT26499WQ-RB DGAT1 Human Ribo-modified Inquiry
SIRGT27499WQ-BB DGAT1 Human Backbone-modified Inquiry

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