siRNA, Anti-DLX1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06165WQ-2OMe)

The product SIRGT06165WQ-2OMe is a type of small interfering RNA (siRNA) that targets DLX1 gene and regulates the expression of gene. The siRNA interferes with the expression of DLX1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001038493.1; NM_178120.4
Related Diseases Dental Fluorosis, Split-Hand/Foot Malformation
Purification HPLC
Target Gene
Gene ID 1745
Uniprot ID P56177
Sub Cat Target Species Modification Scale  
SIRGT07165WQ-2F DLX1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08165WQ-2MOE DLX1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09165WQ-LNA DLX1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06165WQ-RB DLX1 Human Ribo-modified Inquiry
SIRGT07165WQ-BB DLX1 Human Backbone-modified Inquiry

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