siRNA, Anti-DLX3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06167WQ-2OMe)

The product SIRGT06167WQ-2OMe is a type of small interfering RNA (siRNA) that targets DLX3 gene and regulates the expression of gene. The siRNA interferes with the expression of DLX3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005220.2
Alternative Names AI4; TDO
Related Diseases Autosomal dominant conditions trichodentoosseous syndrome
Purification HPLC
Target Gene
Gene ID 1747
Uniprot ID O60479
Sub Cat Target Species Modification Scale  
SIRGT07167WQ-2F DLX3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08167WQ-2MOE DLX3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09167WQ-LNA DLX3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06167WQ-RB DLX3 Human Ribo-modified Inquiry
SIRGT07167WQ-BB DLX3 Human Backbone-modified Inquiry

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