siRNA, Anti-DOK5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41940WQ-2OMe)

The product SIRGT41940WQ-2OMe is a type of small interfering RNA (siRNA) that targets DOK5 gene and regulates the expression of gene. The siRNA interferes with the expression of DOK5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001294161.1
Alternative Names C20orf180; IRS-6; IRS6
Related Diseases Malignant Pheochromocytoma
Purification HPLC
Target Gene
Gene ID 55816
Uniprot ID Q9P104
Sub Cat Target Species Modification Scale  
SIRGT42940WQ-2F DOK5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43940WQ-2MOE DOK5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44940WQ-LNA DOK5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41940WQ-RB DOK5 Human Ribo-modified Inquiry
SIRGT42940WQ-BB DOK5 Human Backbone-modified Inquiry

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