siRNA, Anti-DR1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06214WQ-2OMe)

The product SIRGT06214WQ-2OMe is a type of small interfering RNA (siRNA) that targets DR1 gene and regulates the expression of gene. The siRNA interferes with the expression of DR1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001938.2
Alternative Names NC2; NC2-BETA; NC2B; NCB2
Related Diseases Oesophagostomiasis, Trichostrongylosis
Purification HPLC
Target Gene
Gene ID 1810
Uniprot ID Q01658
Sub Cat Target Species Modification Scale  
SIRGT07214WQ-2F DR1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08214WQ-2MOE DR1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09214WQ-LNA DR1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06214WQ-RB DR1 Human Ribo-modified Inquiry
SIRGT07214WQ-BB DR1 Human Backbone-modified Inquiry

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